| ncRNA name | Cx43 siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | rat retinal Müller cell line rMC-1 |
| Methods | siRNA transfection, Western blot, immunostaining, TUNEL assay, differential staining assay |
| Expression pattern | associated |
| Functional description | When rMC-1 transfected with Cx43 siRNA were grown as cocultures with pericytes, a significant decrease in GJIC, and increase in TUNEL-positive cells was observed, concomitant with decreased Akt phosphorylation. |
| PubMed ID | 24938518 |
| Year | 2014 |
| Title | High glucose alters Cx43 expression and gap junction intercellular communication in retinal Müller cells: promotes Müller cell and pericyte apoptosis. |
| Drug-related ncRNA | NO |
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